Description for Phosphatidylcholine
Lipid Phosphatidylcholine
Species Homo sapiens
 Phosphatidylcholine identified in exosomes derived from the following tissue/cell type
Faeces [Exosomes] 33431899   
Faeces [Exosomes] 33431899   
Melanoma cells [Exosomes/Microvesicles] 23767874   
Placenta [Microvesicles] 23465879   
Placenta [Microvesicles] 23465879   
Placenta [Microvesicles] 23465879   
Plasma [Microparticles] 11878797   
Prostate cancer cells [Exosomes/Microvesicles] 24046871   
Seminal fluid [Prostasomes] 23404715   
Seminal fluid [Prostasomes] 23404715   
 Experiment description of studies that identified Phosphatidylcholine in exosomes
1
Experiment ID1325
Identified moleculeLipid
Identification method HPLC
PubMed ID 33431899   
OrganismHomo sapiens
Experiment descriptionHigh-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
AuthorsKumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year2021
SampleFaeces
Sample nameHealthy volunteers
Molecules identified in the studyProtein
Lipid
Methods used in the studyWestern blotting
Mass spectrometry
Immunofluorescence
HPLC
EV-TRACK -
2
Experiment ID1326
Identified moleculeLipid
Identification method HPLC
PubMed ID 33431899   
OrganismHomo sapiens
Experiment descriptionHigh-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
AuthorsKumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year2021
SampleFaeces
Sample nameType 2 diabetes patients
Molecules identified in the studyProtein
Lipid
Methods used in the studyWestern blotting
Mass spectrometry
Immunofluorescence
HPLC
EV-TRACK -
3
Experiment ID528
Identified moleculeLipid
Identification method Mass spectrometry
PubMed ID 23767874   
OrganismHomo sapiens
Experiment descriptionBiochemical and biological characterization of exosomes containing prominin-1/CD133.
AuthorsRappa G, Mercapide J, Anzanello F, Pope RM, Lorico A.
Journal name Mol Cancer
Publication year2013
SampleMelanoma cells
Sample nameMalignant melanoma (FEMX-I)
Molecules identified in the studyLipids
Methods used in the studyMass spectrometry
EV-TRACK EV130053: EV-METRIC:33%, 33%
4
Experiment ID504
Identified moleculeLipid
Identification method Mass spectrometry
PubMed ID 23465879   
OrganismHomo sapiens
Experiment descriptionLipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes.
AuthorsBaig S, Lim JY, Fernandis AZ, Wenk MR, Kale A, Su LL, Biswas A, Vasoo S, Shui G, Choolani M.
Journal name Placenta
Publication year2013
SamplePlacenta
Sample nameNormal-Placental basal plate/decidua
Molecules identified in the studyLipids
Methods used in the studyMass spectrometry
EV-TRACK -
5
Experiment ID505
Identified moleculeLipid
Identification method Mass spectrometry
PubMed ID 23465879   
OrganismHomo sapiens
Experiment descriptionLipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes.
AuthorsBaig S, Lim JY, Fernandis AZ, Wenk MR, Kale A, Su LL, Biswas A, Vasoo S, Shui G, Choolani M.
Journal name Placenta
Publication year2013
SamplePlacenta
Sample namePreeclampsia-Placental basal plate/decidua
Molecules identified in the studyLipids
Methods used in the studyMass spectrometry
EV-TRACK -
6
Experiment ID506
Identified moleculeLipid
Identification method Mass spectrometry
PubMed ID 23465879   
OrganismHomo sapiens
Experiment descriptionLipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes.
AuthorsBaig S, Lim JY, Fernandis AZ, Wenk MR, Kale A, Su LL, Biswas A, Vasoo S, Shui G, Choolani M.
Journal name Placenta
Publication year2013
SamplePlacenta
Sample nameRecurrent miscarriage-Placental basal plate/decidua
Molecules identified in the studyLipids
Methods used in the studyMass spectrometry
EV-TRACK -
7
Experiment ID365
Identified moleculeLipid
Identification method TLC
PubMed ID 11878797   
OrganismHomo sapiens
Experiment descriptionPhospholipid composition of cell-derived microparticles determined by one-dimensional high-performance thin-layer chromatography.
AuthorsWeerheim AM1, Kolb AM, Sturk A, Nieuwland R.
Journal name Anal Biochem
Publication year2002
SamplePlasma
Sample nameNormal-Plasma
Molecules identified in the studyLipids
Methods used in the studyThin layer chromatography
EV-TRACK -
8
Experiment ID555
Identified moleculeLipid
Identification method Mass spectrometry
PubMed ID 24046871   
OrganismHomo sapiens
Experiment descriptionMolecular lipidomics of exosomes released by PC-3 prostate cancer cells.
AuthorsLlorente A, Skotland T, SylvÃnne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K.
Journal name Biochim Biophys Acta
Publication year2013
SampleProstate cancer cells
Sample namePC3
Molecules identified in the studyLipids
Methods used in the studyMass spectrometry
EV-TRACK EV130205: EV-METRIC:14%
9
Experiment ID499
Identified moleculeLipid
Identification method LC
PubMed ID 23404715   
OrganismHomo sapiens
Experiment descriptionDistinct lipid compositions of two types of human prostasomes.
AuthorsBrouwers JF, Aalberts M, Jansen JW, van Niel G, Wauben MH, Stout TA, Helms JB, Stoorvogel W.
Journal name Proteomics
Publication year2013
SampleSeminal fluid
Sample name100 nm-Seminal fluid
Molecules identified in the studyLipids
Methods used in the studyLiquid chromatography
EV-TRACK EV130034: EV-METRIC:38%
10
Experiment ID500
Identified moleculeLipid
Identification method LC
PubMed ID 23404715   
OrganismHomo sapiens
Experiment descriptionDistinct lipid compositions of two types of human prostasomes.
AuthorsBrouwers JF, Aalberts M, Jansen JW, van Niel G, Wauben MH, Stout TA, Helms JB, Stoorvogel W.
Journal name Proteomics
Publication year2013
SampleSeminal fluid
Sample name50 nm-Seminal fluid
Molecules identified in the studyLipids
Methods used in the studyLiquid chromatography
EV-TRACK EV130034: EV-METRIC:38%